Microbial Technology Research Group

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Summary

Our research activities are centred on both fundamental and applied microbiological and biotechnological approaches, with expertise focused on using living systems and organisms to develop products by utilising a variety of techniques – from protein biochemistry and structural techniques to cell culture. We host a cutting-edge scientific research team that contributes to new discoveries and the development of new methods for practical use.

Product development related to industrial microbiology has been revolutionised with the use of genetically engineered cells. Genetic engineering and gene mounting have been developed in the enhancement of industrial fermentation. Consequently, we are also looking into developing new methods to produce bio-based commercial products by using living organisms. Bioprocessing, Microbiology and Molecular Biology units are two sub-clusters under this research cluster.

The goal of this research cluster is to:

  • Understand and develop biological methods to exploit the properties of bacteria to make useful products using fundamental biotechnology approaches. 
  • Pursue collaborative research with national and international research institutes.

 

Bioprocessing Unit

This research unit focuses on the development of primary and secondary metabolites for industrial applications. Primary focus is given on the upstream and downstream productions of biopolymer, biocatalyst and silver nanoparticles. The current prominence on sustainability, eco-efficiency and green chemistry has generated interest in searching for materials that are renewable and environmentally friendly. 

Polyhydroxyalkanoates (PHAs) are one of the versatile classes of biopolymers with important ecosystem functions and high biotechnological potentials. Our current research focuses on the medical application of PHAs, particularly in the drug delivery system. Application of PHAs in the drug delivery system also signifies a new multidisciplinary approach that combines polymer science and pharmaceutics in the delivery of drugs for the therapeutic treatment. PHA microspheres are prepared for the encapsulation of several drugs such as antibiotics and anticancer. They can serve as a carrier or scaffold supporting more and better cell growth for either injectable purposes or simply supporting cell growth.

Emphasis  has been given on the synthesis of biocatalyst using agro-waste in line with the ‘waste to wealth’ concept. Innumerable enzymes that have numerous applications in industrial processes for food, drug, textile, and dye use have been produced from different types of microorganisms. Development of strains and production of biocatalyst by lowering the production cost have been the main interest of the researchers.

Nanotechnology research is an emerging field and much focus has been given on integrating microbes for the synthesis of nanoparticles. Researchers are working to investigate ways for further integration of this technology to uncover strategies for prevention of antibiotic resistant microbes. 

Researchers

Head of Programme for PhD in Science & Master of Science

Research Interest:

Production of biopolymer using microbial fermentation technology; Development of PHA based microspheres for drug delivery treatment

Senior Lecturer – School of Applied Sciences (SAS)

Research Interest:

Development of silver nanoparticles-based nanocomposite for antimicrobials, Molecular docking study of protein-protein interaction, Enzymatic study.

Microbiology and Molecular Unit

This research unit focuses on the development of primary and secondary metabolites for industrial applications. Primary focus is given on the upstream and downstream productions of biopolymer, biocatalyst and silver nanoparticles. The current prominence on sustainability, eco-efficiency and green chemistry has generated interest in searching for materials that are renewable and environmentally friendly. 

Polyhydroxyalkanoates (PHAs) are one of the versatile classes of biopolymers with important ecosystem functions and high biotechnological potentials. Our current research focuses on the medical application of PHAs, particularly in the drug delivery system. Application of PHAs in the drug delivery system also signifies a new multidisciplinary approach that combines polymer science and pharmaceutics in the delivery of drugs for the therapeutic treatment. PHA microspheres are prepared for the encapsulation of several drugs such as antibiotics and anticancer. They can serve as a carrier or scaffold supporting more and better cell growth for either injectable purposes or simply supporting cell growth.

Emphasis  has been given on the synthesis of biocatalyst using agro-waste in line with the ‘waste to wealth’ concept. Innumerable enzymes that have numerous applications in industrial processes for food, drug, textile, and dye use have been produced from different types of microorganisms. Development of strains and production of biocatalyst by lowering the production cost have been the main interest of the researchers.

Nanotechnology research is an emerging field and much focus has been given on integrating microbes for the synthesis of nanoparticles. Researchers are working to investigate ways for further integration of this technology to uncover strategies for prevention of antibiotic resistant microbes. 

Researchers

Associate Professor & Head of Programme for Bachelor of Science (Hons) in Biotechnology – School of Applied Sciences (SAS)

Research Interest:

Molecular mechanisms of gene expression in PHA producing bacteria; Plastic degrading microorganisms to solve waste problem

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